John A. Abraham, M.D.

Dr. John A. Abraham is the founder of the Orthopaedic Oncology Service at the Rothman Orthopaedic Institute.  He is a nationally recognized orthopaedic oncology surgeon and has 15 years of experience in dealing with bone and soft tissue sarcomas and metastatic cancer to the skeleton.  

Dr. Abraham graduated Magna cum Laude from Harvard University, and then went on to graduate with High Honors from Yale University medical school, where he was inducted into the Alpha Omega Alpha Honor Society.  While at Yale Medical School, Dr. Abraham received the prestigious Nicholas Giarman award for Cancer Research.  He then returned to Harvard to complete an Orthopaedic Surgery residency, where he was selected as the Administrative Chief Resident for two consecutive terms.   He went on to pursue his orthopaedic oncology fellowship at Harvard, based at Massachusetts General Hospital, and Children’s Hospital Boston.  Dr. Abraham was then elected to the faculty of the Dana Farber Cancer Center, one of the leading sarcoma centers in the world, where he served as their primary Orthopaedic Oncologist for 5 years, gaining tremendous experience dealing with very difficult and advanced sarcoma and orthopaedic oncology problems.  During this time, he was also a member of the Arthroplasty service at the Brigham and Women’s Hospital of Harvard Medical School in Boston, and developed significant expertise in joint replacement procedures and advanced revision procedures for failed hip and knee replacements.  Dr. Abraham developed particular expertise in dealing with extensive bone loss of the pelvis, and has become one of the nation’s leading surgeons utilizing custom made patient matched implants for acetabular reconstruction in patients with massive bone loss from failed prior hip surgery.  

Dr. Abraham was recruited to the Rothman Orthopaedic Institute to develop a world class sarcoma and orthopaedic oncology center.  He developed this program from the ground up and then served as the Director of the Jefferson Musculoskeletal Oncology Center at the Kimmel Cancer Center, and Chief of the Rothman Orthopaedic Institute Orthopedic Oncology Service for nearly 10 years, during which time he was an Associate Professor of Orthopedic Surgery and Radiation Oncology at Thomas Jefferson University.  He is currently the Director of Orthopaedic Oncology at the Fox Chase Cancer Center, one of the few NCI designated Comprehensive Cancer centers in the region.  

Dr. Abraham has published numerous scientific articles and book chapters, and has been invited to lecture both nationally and internationally on Sarcoma, with a particular research interest in difficult pelvis sarcoma problems, and revision acetabular joint reconstruction.  He has been named a Top Doctor by Philadelphia Magazine every year for nearly the past 10 years, and is named in America’s Best Doctors list, along with numerous other accolades and honors.  He is a member of the Musculoskeletal Tumor Society and the Connective Tissue Oncology Society.

The joint replacement surgeons at Rothman Orthopaedics collectively perform over 17,000 hip and knee procedures each year in both an inpatient and outpatient capacity. They continue to lead the way in advanced technologies and procedures, providing our patients with the safest, most effective methods to get you back to what you were.  Services offered include:

Hip:

  • Total Hip Replacement
  • Anterior Hip Replacement
  • Minimally Invasive Hip Replacement
  • Rapid Recovery Hip Replacement
  • Revision Hip Replacement
  • Posterior Hip Replacement
  • Computer Assisted Hip Replacement
  • Robotic Hip Replacement
  • Outpatient Total Hip Replacement
  • Anterolateral Approach
  • Direct Lateral Approach

 

Knee:

  • Total Knee Replacement
  • Partial Knee Replacement
  • Revision Knee Replacement
  • Minimally Invasive Knee Replacement
  • Rapid Recovery Knee Replacement
  • Computer Assisted Knee Replacement
  • Robotic Knee Replacement
  • Quad Sparing Knee Replacement
  • Outpatient Total Knee Replacement

 

 

Rothman Physician Spotlight – John A. Abraham, M.D.

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Key Contact Information

Surgical Scheduler (Blue Bell):  484-370-3852

Surgical Scheduler (Newtown):  267-262-6171

Surgical Scheduler (Bordentown):  609-528-3675

Medical Questions:  267-339-3757

Medical Questions for Fox Chase Cancer Center Patients:  215-728-4300

Professional Profile

Education
  • B.A., Harvard University
  • M.D., Yale University
  • Residency, Orthopaedic Surgery, Harvard University
  • Fellowship, Orthopaedic Surgical Oncology Fellowship, Harvard University (Massachusetts General Hospital and Boston's Children Hospital)
Titles & Certifications
  • Board Certified, Orthopaedic Surgery
  • Fellow, American Academy of Orthopaedic Surgeons
Professional Associations
  • American Academy of Orthopaedic Surgeons
  • Musculoskeletal Tumor Society (Elected Member)
  • American Medical Association
  • Connective Tissue Oncology Society (Elected Member)

Publications

Peer Reviewed Bibliography:

x. Shallop B, Starks A, Greenbaum S, Geller DS, Lee A, Ferrone M, Ready JE, Merli G, Abraham JA. Thromboembolic events in patients undergoing intramedullary nailing for metastatic disease to the skeleton. Journal of Bone and Joint Surgery (In preparation for submission)
 
x. Starks A, Shallop B, Greenbaum S, Geller DS, Lee A, Ferrone M, Ready JE, Abraham JA. Outcomes of patients undergoing intramedullary nailing for metastatic disease to the skeleton. Journal of Bone and Joint Surgery (In preparation for submission)
 
x. Shallop, B, O’Hara B, Miettenin M, Morrison W, Abraham JA. Pseudomyogenic Hemangioendothelioma of bone. Clin Orthop Relat Res (In preparation for submission)
 
x.Shallop B, Starks A, Morrison W, Deeley D, Zoga A, Long S, Conliffe T, Abraham JA Hemangiomas of the spine. Spine (In preparation for submission)
 
x. Erstad D, Baldini EH, Abraham JA, Ferrone ML, Ready JE, Raut, CP. Indications for amputation in extremity sarcoma. Annals of Surgical Oncology (In preparation for Submission)
 
x. Kirsch J, Rosenberg AE, O’Hara B, Morrison W, Abraham JA. Aggressive Chondromyxoid Fibroma in an Elderly Man. Clin Orthop Relat Res (Submitted)
 
x. Abraham JA, Shallop B, Geller DS. Surgical Outcomes of Patients Treated with Computer Navigated Resection of Pelvis Sarcoma. Sarcoma (Submitted)
 
1. Shallop B, Abraham JA. Synovial Chondromatosis of the pes anserine bursa secondary to underlying osteochondroma. Orthopedics. (Accepted, awaiting publication)
 
2. Ghanem E, Heppert V, Spangehl M, Abraham JA, Azzam K, Barnes L, Burgo FJ, Ebeid W, Goyal N, Guerra E, Hitt K, Kallel S, Klein G, Kosashvili Y, Levine B, Matsen L, Morris MJ, Purtill JJ, Ranawat C, Sharkey PF, Sierra R, Stefansdottir A. Wound Management. J Arthroplasty. 2013 Dec 15. pii: S0883-5403(13)00722-5. doi: 10.1016/j.arth.2013.09.041.
 
3.Offodile A, Abraham JA, Guo L. B Novel technique for reconstruction of large abdominal wall defects using bio-prosthetic mesh. Hernia (Accepted, awaiting publication)
 
4. Wong J, Abraham JA. Upper Extremity Considerations for Musculoskeletal Tumor Surgery. Orthopedic Clinics North America (Accepted, awaiting publication)
 
5. Starks A, Guo L, Abraham JA. Resection of Soft Tissue Tumors Extending Thorough the Obturator Foramen. Orthopedics. 2013 Sep;36(9):e1220-4. doi: 10.3928/01477447-20130821-29.
 
6. Karanjia H, Abraham JA, O’Hara B, Shallop B, Daniels J, Taweel N, Schick F. Distal Fibula Metastasis from Cholangiocarcinoma. J Foot Ankle Surg. 2013 Apr 8. pii: S1067-2516(13)00071-9. doi: 10.1053/j.jfas.2013.02.017. 2013
 
7. Maceroli M,Ponnanpan R, Shallop B, Vaccaro A, Abraham JA. “Sacral Osteochondroma Causing Radiculopathy” Journal of Bone and Joint Surgery, Case Connector Volume 3(3) July 2013
 
8. Zhang I, Zaorsky N, Abraham JA, Tuluc M, Curry JM, Bar-Ad V. Chondrosarcoma of the hyoid bone: case report and a review of current management options. Head Neck. 2013 May 29. doi: 10.1002/hed.23373.
 
9. Lall A, Hohn E, Kim MY, Gorlick RG, Abraham JA, Geller DS. Comparison of Surface Area across the Allograft-Host Junction Site Using Conventional and Navigated Osteotomy Technique. Sarcoma. 2012;2012:197540. doi: 10.1155/2012/197540. Epub 2012 Dec 18.
 
10. Baldini EH, Lapidus MR, Wang Q, Manola J, Orgill DP, Pomahac B, Marcus KJ, Bertagnolli MM, Devlin PD, George S, Abraham JA, Ferrone ML, Ready JE, Raut, CP. Predictors for Major Wound Complications Following Preoperative Radiotherapy and Surgery for Soft-Tissue Sarcoma of the Extremities and Trunk: Importance of Tumor Proximity to Skin Surface. Ann Surg Oncol
DOI 10.1245/s10434-012-2797-1
 
11. Abraham JA, Weaver MJ, Raskin KA, Ready JR, O’Brien EL, Hornicek FJ. Short-Term Outcomes of Cementless Modular Endoprostheses in Lower Extremity. Current Orthopedic Practice, 23(3):213-217 May/June 2012
 
12. Abraham JA, Weaver MJ, Hornick JL, Zurakowski D, Ready JE. Outcomes and prognostic factors for a consecutive case series of 115 patients with non-visceral leiomyosarcoma. Journal of Bone and Joint Surgery, 94-A(8) 736-43 April 18, 2012
13. Abraham JA. Recent advances in navigation-assisted musculoskeletal tumor resection. Current Orthopedic Practice. 22(4):297-302,July/August 2011.
14. Banffy M, Vrahas M, Ready JE, Abraham JA. Conservative versus Prophylactic Management in the Treatment of Bisphosphonate-Associated Femoral Stress Fractures. Clin Orthop Relat Res. 2011 Jul;469(7):2028-34.
 
15. Abraham JA. Computer Aided Surgical Navigation: A Novel technique to Assist in Resection and Reconstruction of Malignant Pelvis Tumors, Orthopaedic Knowledge Online, July 2011 http://orthoportal.aaos.org/emedia/abstract.aspx?resource=EMEDIA_ONC023
 
16. Abraham JA, Butrynski J, Baldini EH, Management of Adult Extremity and Trunk Soft Tissue Sarcoma, Expert Review of Anticancer Therapy, Feb 2010 Vol 10(2):233-48
 
17. Elco CP, Marino-Enriquez A, Dal Cin P, Abraham JA, Hornick JL. Hybrid Myxoinflammatory Fibroblastic Sarcoma/Hemosiderotic Fibrolipomatous Tumor: Report of a Case Providing Further Evidence for a Pathogenetic Link. American Journal of Surgical Pathology. Nov 2010;34(11):1723-7.
 
18. Pozdnyakova O, Abraham JA, Freedman AS, Kutok JS  Epstein-Barr Virus-Associated Diffuse Large B-Cell Lymphoma in an Immunocompetent Woman, Journal of Clinical Oncology, Nov 2009
 
19. Kaufman AM, Abraham JA, Kattapuram S, Rosenthal D, Hornicek FJ. Chronic multifocal chest and leg pain in a 34-year old woman. Clinical Orthopedics and Related Research. 467(4)1112-7 Apr 2008
 
20. Weaver, MJ, Abraham JA Leiomyosarcoma of Bone and Soft Tissue, Electronic Sarcoma Update Newsletter, Vol. 4(2). April 2007
 
21. Abraham JA, Hornicek FJ, Kaufman AM, Harmon DC, Springfield DS, Raskin KA, Mankin HJ, Kirsch DG, Rosenberg AE, Nielsen GP, Deshpande V, Suit HD, Delaney TF, Yoon SS. Treatment and outcome of 82 patients with angiosarcoma. Annals of Surgical Oncology, 14(6):1953-67 Jun 2007
 
 

Non-Peer Reviewed Bibliography:

Ames J, Abraham JA, Geller D, Goldsmith J, Gebhardt M, Proximal Tibial Lesion in a Young Adult: Early Diagnosis and a Novel Treatment. Harvard Orthopaedic Journal, July 2006
 
Abraham JA. The Massachusetts General Hospital Experience with Angiosarcoma: Survival Analysis. Harvard Orthopaedic Journal. Oct 2005
 

Reviewer:

Clinical Orthopedics and Related Research
Orthopedics
Journal of Surgical Oncology
Annals of Surgical Oncology
 
 

Books:

Abraham JA, editor. Current Trends in Orthopedic Oncology. World Clinics in Orthopedic Oncology. JayPee Publishers. New Delhi, India. In preparation, Expected publication March 2014
 
 

Chapters:

Abraham JA, Verma K Complications of sacropelvic reconstructions for tumor resection, Complicartions of Spinal Instrumentation. Vaccaro A, Kim D, Radcliff K, eds. Thieme Publishers, New York, NY. (In progress)
 
Abraham JA, Wound Management, in International Consensus Meeting on Periprosthetic Joint Infection, Parvizi J, Gerhke T, eds. DataTrace Publishing,
 
Abraham JA, Hornicek FJ. Chordoma, in Current Trends in Orthopedic Oncology. World Clinics in Orthopedic Oncology. JayPee Publishers. New Delhi, India. Expected publication March 2014
 
Abraham JA. Recent Advances in Surgical Treatment for Sarcoma, in Current Trends in Orthopedic Oncology. World Clinics in Orthopedic Oncology. JayPee Publishers. New Delhi, India. Expected publication March 2014
 
Abraham JA, Gutowski C, Hornicek FJ. Chondrosarcoma, in Current Trends in Orthopedic Oncology. World Clinics in Orthopedic Oncology. JayPee Publishers. New Delhi, India. Expected publication March 2014
 
Shallop B, Abraham JA Hip Disarticulation, in The Hip: Preservation, Replacement, and Revision. Parvizi J, Goyal N, Cashman J ed. DataTrace Publishing, In Press
 
Abraham JA, Neuman B, Hornicek FJ Chordoma, in The Intervertebral Disc. Shapiro I, Risbud M, eds. Springer-Verlag, Sept 2013
 
Abraham JA Benign Cystic Bone Lesions, in Orthopedic Knowledge Update: Musculoskeletal Tumors 3. American Academy of Orthopedic Surgeons Publications. In Press
 
Abraham JA Musculoskeletal Oncology, in Orthopedic Knowledge Update 11. American Academy of Orthopedic Surgeons Publications, In Press
 
Abraham JA ,Gebhardt, M., Pediatric Musculoskeletal Tumors about the Knee, in The Pediatric and Adolescent Knee, Micheli, L.J., and Kocher, M. eds. Saunders, Philadelphia 2006
 
Abraham JA, Gebhardt, M, Malignant Bone Tumors, in Tachdjian’s Pediatric Orthopedics, 4th ed. Herring, JA ed. Elsevier 2007
 
 

Lectures by Invitation:

Local:
 
May 2014. “Avoiding getting into trouble with bone and soft tissue lesions” Pennsylvania Orthopedic Society Meeting, Hershey PA
 
May 2014. “Orthopedic Oncology Update for the Resident”, UMDNJ-Rowan SOM, Stratford, NJ
 
May 2013. “Metastatic Disease to the Skeleton” Methodist Hospital Grand Rounds, Philadelphia PA
 
May 2013. “Extreme Orthopedics” Rothman Orthopaedic Institute Community Physicians Lecture, Philadelphia PA
 
April 2013 “Benefits of Joint Replacement” Watermark Rehabilitation Center, Philadelphia PA
 
June 2012. “Update on Management of Sarcoma” Holy Redeemer Hospital Grand Rounds, Allentown PA
 
September 2010. “Management of Soft Tissue Sarcoma” Jefferson Hospital Grand Rounds, Philadelphia PA
 
May 2010 “Update on Bone and Soft Tissue Sarcoma” Mercy-Fitzgerald Hospital Grand Rounds, Philadelphia PA
 
April 2010 “Current Management of Soft Tissue Sarcoma” Riddle Hospital Grand Rounds, Media PA
 
September 2009 “Update on Management of Skeletal Metastases” Fall River Cancer Center, MA
 
Jan 2008 “Computer Assisted Surgery in Pelvic Tumor Surgery.” Grand Rounds, Harvard Medical School
 
National:
 
January 2013 “Future Developments in Limb Salvage Surgery” Biomet Limb Salvage Meeting Salt Lake City, UT
 
Sept 2011 “Overview of Soft Tissue Sarcoma Management” Inter-Urban Orthopedic Society, Philadelphia, PA
 
July 2009 “New Approaches to Metastatic Disease to the Skeleton” Breast Cancer Management, Boston, MA
 
September 2008 “Management of Adult Sarcoma” American Society for Therapeutic Radiation and Oncology (ASTRO) 50th Annual meeting, Boston MA
 
Dec 2005 “Angiosarcoma” Duke University Orthopedic Grand Rounds, Raleigh, NC
 
International:
 
Feb 2009. “Use of Massive Allografts in Orthopedic Surgery” Orthopedic Surgery Grand Rounds, McGill University, Montreal, Canada.
 
 

Abstracts, Posters, Presentations:

Thromboembolic events in patients undergoing surgery for skeletal metastases (Poster) AAOS 2014
 
Intramedullary Nailing without cementation for skeletal metastases (Podium) AAOS 2014
 
Synovial condromatosis of Pes Anserine bursa secondary to tibial osteochondroma. (Poster) EOA 2013
 
Intramedullary nailing without cementation for skeletal metastases. (Podium) EOA 2013
 
Hemangioma of the vertebral column. (Poster) MSTS 2013.
 
Intramedullary nailing without cementation for skeletal matastases. (Poster) MSTS 2013
 
Thromboembolic events in patients undergoing surgery for skeletal metastases. (Poster) MSTS 2013
 
Sacral Osteochondroma causing radiculopathy (Poster) MSTS 2013
 
Effect of Needle type on quality of Core needle biopsy (Poster) MSTS 2013
 
Two year follow up of Navigation assisted pelvic tumor resection. (Poster) MSTS 2013
 
Efficacy of Synovial Biopsy. (Poster) MSTS 2013
 
Canoe Technique for allograft reconstructions: A variation on a theme. (Poster) MSTS 2013
 
Hemangioma of the vertebral column. (Poster) ISOLS 2013.
 
Intramedullary nailing without cementation for skeletal matastases. (Poster) ISOLS 2013
 
Thromboembolic events in patients undergoing surgery for skeletal metastases. (Poster) ISOLS 2013
 
Epithelioid Sarcoma-like Hemangioendothelioma (ESHLE) of bone (Poster) ISOLS 2013
 
Canoe Technique for allograft reconstructions: A variation on a theme. (Poster) ISOLS 2013
 
Total joint arthroplasty in patients with prior history of cancer. (Podium) American Academy of Orthopedic Surgery (AAOS) March 2013
 
Complex tibial plateau nonunion treated with total knee arthroplasty. (Poster) Philadelphia Trauma Symposium, June 2013
 
Intramedullary nail stabilization of impending and completed pathologic fractures without curettage or cementation. (Poster) Philadelphia Trauma Symposium, June 2013
 
Total joint arthroplasty in patients with cancer. (Podium) Eastern Orthopedic Association (EOA) June 2012
 
Treatment of pigmented villonadular synovitis of the hip with surgical dislocation and total synovectomy. (Abstract) Connective Tissue Oncology Society (CTOS) 2012
 
Navigation-assisted joint sparing proximal tibial resection and allograft reconstruction for clear cell chondrosarcoma in a 14 year old. (Abstract) CTOS 2012
 
Epithelioid sarcoma-like hemangioendotheilioma can occur in bone. (Abstract) CTOS 2012
 
Two year follow up of six navigation assisted pelvis/sacrum bone sarcoma resections. (Abstract) CTOS 2012
 
HIF-1 signaling in chordoma is identical to nucleus pulposus cells and confers survival advantage in hypoxic environment. (Poster Discussion), CTOS 2012
 
Surface Area across Osteosynthesis Site in Bulk Allograft Reconstruction. (Poster) International Society of Limb Salvage (ISOLS) Sept 2011
 
Effect of Navigation on contact surface area of long bone osteotomies. (Poster) Musculoskeletal Tumor Society(MSTS)/CTOS Combined Meeting Oct 2011
 
Predictors for major wound complications following pre-operative radiotherapy and surgery for soft tissue sarcoma of the extremity and trunk: importance of proximity to the skin surface. (Podium) MSTS/CTOS Oct 2011
 
Surface Area across Osteosynthesis Site in Bulk Allograft Reconstruction. (Poster) EOA Oct 2011
 
Short term results of computer assisted navigation for pelvis sarcoma resection. (Podium) MSTS, Sept 2010
 
PEComa of Bone: Treatment and three year follow up of a patient with a newly described sarcoma subtype occurring in bone. (Poster) MSTS Sept 2010
 
Surgical treatment of soft tissue tumors extending through the obturator ring of the pelvis.  (Poster) MSTS Sept 2010
 
Intra-cardiac metastasis from calf soft tissue sarcoma: treatment and follow up of an unusual metastatic pattern. (Poster) MSTS Sept 2010
 
Soft tissue tumors of the pelvis extending through the obturator ring. (Poster) CTOS Nov 2010
 
Cementless Endoprosthetic Reconstruction in the Treatment of Lower Extremity Malignant Bone Tumors. (Podium) AAOS March 2009
 
Computer Aided Navigation Surgery can be used for Resections of the Pelvis. (Podium) MSTS Sept 2009
 
Outcomes of 115 patients with Leiomyosarcoma. (Poster) CTOS Nov 2009
 
Computer-Aided Navigation for Malignant Pelvis Tumors. (Poster) CTOS Nov 2009
 
Leiomyosarcoma of Soft Tissue and Bone: A single center 10 year experience. (Poster) MSTS June 2007
 
Predictors of overall survival in Angiosarcoma. (Poster) MSTS June 2006
 
 

Grant Support:

x. Abraham JA American Cancer Society-Institutional Research Grant. “HIF-1 is necessary for Chordoma cell survival in hypoxic microenvironment.” (Application Submitted March 2014) Decision Pending
 
Abraham JA The Angiogenesis Foundation Fellowship Grant. Funding for medical school thesis, “Mutations in yeast Methionine Aminopeptidase-2 interfere with binding of the anti-angiogenic agent fumagillin” The Angiogenesis Foundation Cambridge, MA Sept 1997. COMPLETED
 
Abraham JA Brigham and Women’s Hospital Musculoskeletal Translational Research Grant. Funding for development of Orthopedic Oncology database linked to specimen tumor bank. Brigham and Women’s Hospital Jan 2007. COMPLETED
 

 

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