Ryan A. Durfee, MD

To schedule an appointment with Dr. Durfee, please call 844-407-4070.

Dr. Durfee is a board-certified orthopaedic surgeon who specializes in musculoskeletal oncology. He diagnoses, treats and removes malignant tumors of the bone, soft tissue and nerves, including cancers that have spread to the bone causing debilitating pain and fractures. He also provides expert care for a variety of orthopaedic injuries including the management of complex fractures with and without the presence of a tumor.

Dr. Durfee’s approach to care includes acting as the point person for his patients’ treatment planning, ensuring thorough communication among multidisciplinary medical team members. He has a strong interest in regenerative medicine and actively explores novel approaches to disease while placing an emphasis on patient education and the need to tailor therapies according to the needs of each individual.

Dr. Durfee is an Orlando native and is happy to continue to call Orlando home.  An honors graduate of the University of Notre Dame, he earned his medical degree at the University of Miami Miller School of Medicine. He thereafter undertook his orthopaedic surgery residency at Orlando Health, where he was honored with an award for clinical and research excellence. He next completed a highly selective fellowship in musculoskeletal oncology at the University of Chicago.

Dr. Durfee joined AdventHealth’s partnership practice with Rothman Orthopedics after practicing for five years at Miami’s Institute for Orthopaedic Innovations. He has published research articles on musculoskeletal tumors and metastatic disease. He is an active candidate member of the American Academy of Orthopedic Surgery and the Musculoskeletal Tumor Society and active in the Florida Orthopedic Society.

Office Locations

Surgical Locations

    Professional Profile

    • MD, The University of Miami Miller School of Medicine, Miami, FL
    • Residency, Orthopaedic Surgery, Orlando Health, Department of Orthopaedic Surgery, Orlando, FL
    • Fellowship, Musculoskeletal Oncology, University of Chicago Medicine and Biological Sciences, Chicago, IL
    Titles & Certifications
    • Board Certified, American Board of Orthopaedic Surgery
    Professional Associations
    • American Academy of Orthopaedic Surgeons
    • Musculoskeletal Tumor Society
    • Florida Orthopaedic Society
    • Mercy Hospital Cancer Committee


    Sassoon A, Durfee RA, Langford JL, Koval, K, Haidukewych GJ. Semi-Elective Treatment of Open Tibial Shaft Fractures with Intramedullary Nail Fixation and Primary Wound Closure, Is it Safe? Manuscript awaiting submission.

    Durfee RA, Sabo S, Binitie O, Letson GD, Cheong DA. Percutaneous Acetabuloplasty for Metastatic Lesions. Orthopedics. 2017 Jan 1;40(1):e170-e175. doi: 10.3928/01477447-20161017-05. Epub 2016 Oct 27. PMID: 27783835

    Durfee RA, Mohammed M, Luu H. Review of Osteosarcoma and Current Management. Rheumatol Ther. 2016 Dec;3(2):221-243. PMID:27761754

    Reddy MP, Mosenthal WP, Lee CS, Durfee RA, Pytel P, Luu HH. Rare Epstein-Barr Virus Associated Smooth Muscle Tumor in a Patient with AIDS: A Case Report. JBJS Case Connect. 2020 Jan-Mar;10(1):e0210. doi: 10.2106/JBJS.CC.19.00210. PMID: 32224643

    Temple HT, Durfee RA, et al. Nova Southeastern University Biorepository
    Specimen collection underway.

    Authored Stories

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