Clinical Trials

Rothman Orthopaedic Institute has a world-class research facility and department whose focus is to improve patient care through evidence-based research. The staff of 36 works everyday on clinical trials, investigator-initiated studies, and database research utilizing a database which contains data from over a million patients. This database has been developed for over a decade and is a powerful tool that the Rothman Orthopaedic Institute has over other Orthopaedic groups in the area and the nation. We use this data to develop targeted-research studies and clinical trials with a focus on Joint, Spine, Shoulder, Sports, Foot and Ankle, Hand, Trauma, Orthopaedic Oncology, and Infection studies. These studies are all designed to help improve treatment, infection prevention, and recovery.

2023

Sutures for Treatment of Knee Arthroscopy

April 21, 2023

Conditions: Knee Arthroscopy; Suture
Interventions: Device: 3.0 monocryl suture; Device: 3.0 nylon suture
Sponsor: Rothman Institute Orthopaedics
Completed

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Clinical Trials

2023

Sutures for Treatment of Knee Arthroscopy

Pain Relief After PrimaryTKA

Is Physical Therapy Clearance Before Arthroplasty Home Discharge Necessary?

2022

Low Dose Dexamethasone for Distal Radius Fractures

Antibiotic Loaded Cement After TKA

Post Operative Pain Management for ACL Reconstruction

Joint Microbiome Study for the Knee

Treatment of Tendinosis Using the TenJet Hydroresection System

Diagnosing Compartment Syndrome With SHAPE vs Elastography

InSpace Accelerated Rehabilitation Study

2021

Weight Bearing for Fibular Fractures

Effect of Postoperative Ketorolac on Bone Healing After Joint Fusion

Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction

Evaluation of Surgical Positioning in Arthroscopic Shoulder Stabilization

Pain Management After Surgery

NGS for Spine Surgery Patients

Effect of Ropivacaine During Popliteal Nerve Block in Foot and Ankle Surgery

Pain Management After Shoulder Arthroplasty

Traditional PT v Internet Based PT After Total Knee Arthroscopy

TSA Versus RSA in Patients >75

Safe Return to Play After ACL Reconstruction

Does Meloxicam Provide as Much Pain Relief as Opioids After Shoulder Surgery?

Or v IV Antibiotics for Infection

Saphenous Nerve Block for Partial Meniscectomy

2020

Trial of Weight Bearing Status Following Femoral Revision With Tapered, Fluted, Titanium Stems

Sleep Quality and Pain Medication Use Following Arthroscopic Rotator Cuff Repair

Opioid-Free Study in Arthroscopic Rotator Cuff Repair

Probiotics Pilot Project

Regeneten Patch vs Standard Care in Partial Thickness Rotator Cuff Repair

S. Aureus Translocation From Skin and Nose to Periprosthetic Tissues

Zonulin Biomarker for Diagnosis of Hip and Knee Infections

Hand Incision Study

Music in Wide Awake Hand Surgery

Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis

Prospective Evaluation of Oral Antibiotics for Treatment of Shoulder PJI

A Study Evaluating Splinting and Casting for Distal Radius Fractures in the Elderly

The Effect of Tranexamic Acid (TXA) on Visualization During Shoulder Arthroscopy

The Impact of Smoking on Outcomes and Complications in Total Joint Arthroplasty: A Prospective Crossover Study

Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty

A Study to Evaluate the Outcomes of Cannabinoid (CBD) Roll-on Topical Stick in Primary Total Knee Arthroplasty

Addition of Muscle Relaxants in a Multimodal Analgesic Regimen for Analgesia After Primary Total Knee Arthroplasty

Randomized Trial of Intraoperative IV Versus Preoperative Oral Acetaminophen During Ambulatory Lumbar Discectomy

MSSA and MRSA Screening in Patients Undergoing Elective TJA: the Benefits of Next-generation Sequencing

Do Relaxation Exercises Decrease Postoperative Pain After Arthroscopic Rotator Cuff Repair?

Caffeine Study for Pain Control Following Total Joint Replacement

Return to Play Checklist

Opioids Following ACL

Leukocyte Esterase Sensor Test

Comparison of Intravascular Uptake and Pain Perception During Epidural Injection Using 22 Gauge vs 25 Gauge Needle

Use of Cooled Radiofrequency for the Treatment of Hip Pain Associated With Hip OA Compared to Intra-articular Steroid Injections

Post-Approval Study Protocol for the Simplify Cervical Artificial Disc

2019

Opioid Counseling Following Orthopaedic Surgery

The Effect of Prolonged Multimodal Analgesic Regimen on Post Hospital Discharge Opioid Use and Pain Control After Primary Total Knee Arthroplasty

NGS for Non-unions

Fixed Inclination Humeral Cut

Telehealth Following Orthopaedic Procedures

Post-op Ketamine Study

Comparing Ropivacaine Adductor Canal Blockade by Surgeon Versus Anesthesiologist

Microfracture vs. Microfracture and BMAC for Osteochondral Lesions of the Talus

Dual Mobility Acetabular Cups in Revision TJA

Post-operative Exparel Study Following Rotator Cuff Repair

Knee Kinematics for Subjects With Zimmer-Biomet Posterior Cruciate Retaining or Posterior Stabilizing Total Knee Arthroplasty

Dual Mobility in "High Risk" Patients

Long Term Sidus PMCF

Transforaminal Lumbar Interbody Fusion (TLIF)

DIFFIR - Geriatric Distal Femur Fixation Versus Replacement

2018

Effect of Toradol on Post-operative Foot and Ankle Healing

The Need for Compression Bandage Following Total Knee Arthroplasty A Prospective Randomized Controlled Trial Conducted in Simultaneous Bilateral Total Knee Replacements

Randomized, Controlled Trial of Posterior C1-2 Fusion Versus Bracing Alone for Treatment of Type II Odontoid Process Fractures in the Elderly

Does the Addition of Hydrogen Peroxide to Chlorhexidine Skin Prep to Treat P. Acnes in the Shoulder

Use of Cooled Radiofrequency for the Treatment of Hip Pain Associated With OA of the Hip Compared to Intra-articular Steroid Injections