Mark Wang, M.D., PhD

Dr. Wang is an Associate Professor at Sidney Kimmel Medical College, Thomas Jefferson University and has a special focus on the treatment of Hand and Wrist disorders.  After graduating from Cornell University with a degree in Mechanical Engineering, he was selected to the MD, PhD Program at Thomas Jefferson University.  Raised in Bryn Mawr, PA, he is a Radnor High School alumnus. 

 

Professional Profile

Education
  • B.S., Cornell University
  • M.D., Thomas Jefferson University
  • Ph.D., Thomas Jefferson University
  • Internship, General Surgery, University of California, San Diego
  • Residency, Orthopaedic Surgery, University of California, San Diego
  • Fellowship, Orthopaedic Hand Surgery, The Philadelphia Hand Center
Titles & Certifications
  • Board Certified, Orthopaedic Surgery
  • American Association for Hand Surgery (AAHS)
  • American Society for Surgery of the Hand (ASSH)
  • American Medical Association (AMA)
  • American Academy of Orthopaedic Surgeons (AAOS)
  • American Society of Cell Biology (ASCB)
  • Orthopaedic Research Society (ORS)
  • Certificate of Added Qualification in Hand Surgery
Highlights & Achievements
  • Eastern Orthopaedic Association Travel Grant, Outstanding Scientific Contribution, 42nd Annual Meeting, Eastern Orthopaedic Association, Williamsburg, VA
  • James B. Peake Award, Outstanding Clinical Service to U.S. Veterans, Department of Veterans Affairs, San Diego, CA
  • AOA-OREF Resident Leadership Forum, 7th Annual Meeting, The American Orthopaedic Association and Orthopaedic Research and Education Foundation, Bonita Springs, FL
  • Best Paper, Resident Research Day 2006, Combined Meeting UCSD and Naval Medical Center of San Diego, San Diego, CA
  • Dubbs Scholar Award, Thomas Jefferson University
  • Alumni Travel Fellowship Award, Thomas Jefferson University
  • Intramural Research Training Award, National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health

Publications

Publications:
1.    Beredjiklian PK, Wang M, Lutsky K, Vaccaro A, Rivlin M. Three-Dimensional Printing in Orthopaedic Surgery: Technology and Clinical Applications. J Bone Joint Surg Am. 2020 Feb 19;. doi: 10.2106/JBJS.19.00877. [Epub ahead of print] PubMed PMID: 32079880.
2.    Sandrowski K, Edelman D, Rivlin M, Jones C, Wang M, Gallant G, Beredjiklian PK. A Prospective Evaluation of Adverse Reactions to Single-Dose Intravenous Antibiotic Prophylaxis During Outpatient Hand Surgery. Hand (N Y). 2020 Jan;15(1):41-44. doi: 10.1177/1558944718787264. Epub 2018 Jul 15. PubMed PMID: 30009635; PubMed Central PMCID: PMC6966299.
3.    Poiset S, Abboudi J, Gallant G, Jones C, Kirkpatrick W, et al. Splinting after Distal Radius Fracture Fixation: A Prospective Cohort Analysis of Postoperative Plaster Splint versus Soft Dressing. J Wrist Surg. 2019 Dec;8(6):452-255. Epub 2019 May 27. PubMed PMID: 31815058.
4.    Martin DP, Chapman T, Williamson C, Tinsley B, Ilyas AM, Wang ML. Elevated Radiation Exposure Associated With Above Surface Flat Detector Mini C-Arm Use. Hand (N Y). 2019 Jul;14(4):565-569. doi: 10.1177/1558944717743600. Epub 2017 Nov 22. PubMed PMID: 29166785; PubMed Central PMCID: PMC6760076.
5.    Voskeridjian AC, Calem D, Rivlin M, Beredjiklian PK, Wang ML. An Evaluation of Complications Following Ultrasound-Guided Regional Block Anesthesia in Outpatient Hand Surgery. Hand (N Y). 2019 Jun 10. [Epub ahead of print]. PubMed PMID: 31179730.
6.    Okoli M, Silverman M, Abboudi J, Jones C. Kirkpatrick W, et al.  Radiographic Healing and Functional Outcomes of Untreated Ulnar Styloid Fractures Following Volar Plate Fixation of Distal Radius Fractures: A Prospective Analysis. Hand (N Y). 2019 Jul 9:1558944719855445. [Epub ahead of print] PubMed PMID: 31286791.
7.    Said J, Abboudi J, Gallant G, Jones C, Kirkpatrick W, et al. Prospective evaluation of sleep improvement after cubital tunnel decompression surgery. J Shoulder Elbow Surg. 2019 May;28(5):e144-e149. Epub 2019 Jan 23. PubMed PMID: 30685275.
8.    Tulipan JE, Kachooei AR, Shearin J, Braun Y, Wang ML, et al. Ultrasound Evaluation for Incomplete Carpal Tunnel Release. Hand (N Y). 2019 Mar 12. [Epub ahead of print]. PubMed PMID: 30857423.
9.    Hozack BA, Abboudi J, Gallant G, Jones CM, Kirkpatrick W, et al. Prospective Evaluation of Opioid Consumption Following Cubital Tunnel Decompression Surgery. Hand (N Y). 2019 Jan;14(1):42-47. Epub 2018 Sep 29. PubMed PMID: 30269520.
10.    Graham JG, Wang ML, Rivlin M, Beredjiklian PK. Biologic and mechanical aspects of tendon fibrosis after injury and repair. Connect Tissue Res. 2019 Jan;60(1):10-20. Epub 2018 Sep 7. PubMed PMID: 30126313.
11.    Wang ML, Rivlin M, Graham JG, Beredjiklian PK. Peripheral nerve injury, scarring, and recovery. Connect Tissue Res. 2019 Jan;60(1):3-9. Epub 2018 Sep 6. PubMed PMID: 30187777.
12.    Chapman T, Martin DP, Williamson C, Tinsley B, Wang ML, et al. Mini C-Arm Fluoroscopy: Does Its Configuration Matter for Radiation Exposure to the Surgeon? Hand (N Y). 2018 Sep;13(5):552-557. PubMed PMID: 28643518; PubMed Central PMCID: PMC6109895.
13.    Graham J, Wang M, Frizzell K, Watkins C, Beredjiklian P, et al. Conventional vs 3-Dimensional Printed Cast Wear Comfort. Hand (N Y). 2018 Aug 27;1558944718795291. PubMed PMID: 30146902.
14.    Wang ML, Beredjiklian PK, Steplewski A, Fertala J, Fertala A. Engineering the Second Generation of Therapeutic Cells with Enhanced Targeting of Injured Tissues. Tissue Eng Part A. 2018 Aug;24(15-16):1293-1300. PubMed PMID: 29478375.
15.    Chen A, Fertala A, Abboud J, Wang M, Rivlin M, et al. The Molecular Basis of Genetic Collagen Disorders and Its Clinical Relevance. J Bone Joint Surg Am. 2018 Jun 6;100(11):976-986. PubMed PMID: 29870450.
16.    Miller AJ, Livesey M, Martin DP, Abboudi J, Kirkpatrick WH, et al. Thumb Basal Joint Arthroplasty: Prospective Comparison of Perioperative Analgesia and Opioid Consumption. Orthopedics. 2018 May 1;41(3):e410-e415. PubMed PMID: 29658975.
17.    Rivlin M, Kachooei AR, Wang ML, Ilyas AM. Electrodiagnostic Grade and Carpal Tunnel Release Outcomes: A Prospective Analysis. J Hand Surg Am. 2018 May;43(5):425-431. PubMed PMID: 29396311.
18.    Miller AJ, Tulipan JE, Wang ML, Beredjiklian P, Fertala A, et al. A Peripheral Nerve Injury Model Utilizing a Simple Tissue Sparing Approach to the Rabbit Sciatic Nerve. Journal of Musculoskeletal Research. 2018 March 07; 21(1):1850002.
19.    Martin DP, Wilt ZT, Cantlon MB, Wang ML. Controversies Surrounding the Management of the Isolated Type-II Radial-Head Fracture. JBJS Rev. 2017 Dec;5(12):e3. PubMed PMID: 29232266.
20.    Tulipan JE, Kim N, Abboudi J, Jones C, Liss F, et al. Open Carpal Tunnel Release Outcomes: Performed Wide Awake versus with Sedation. J Hand Microsurg. 2017 Aug;9(2):74-79. PubMed PMID: 28867906; PubMed Central PMCID: PMC5579466.
21.    Rivlin M, Miller A, Tulipan J, Beredjiklian PK, Wang ML, et al. Patterns of production of collagen-rich deposits in peripheral nerves in response to injury: A pilot study in a rabbit model. Brain Behav. 2017 Jul;7(7):e00659. PubMed PMID: 28729925; PubMed Central PMCID: PMC5516593.
22.    Tulipan JE, Kim N, Abboudi J, Jones C, Liss F, et al. Prospective Evaluation of Sleep Improvement Following Carpal Tunnel Release Surgery. J Hand Surg Am. 2017 May;42(5):390.e1-390.e6. PubMed PMID: 28359641.
23.    Steplewski A, Fertala J, Beredjiklian PK, Abboud JA, Wang MLY, et al. Blocking collagen fibril formation in injured knees reduces flexion contracture in a rabbit model. J Orthop Res. 2017 May;35(5):1038-1046. PubMed PMID: 27419365.
24.    Wang ML, Hoffler CE, Ilyas AM, Beredjiklian PK, Leinberry CF. Fluoroscopic Exposure With Use of Mini-C-Arm During Routine Hand Surgery: A Prospective Comparison of Hand Versus Eye Radiation Dosage. J Surg Orthop Adv. Summer 2017;26(2):102-105. PubMed PMID: 28644122.
25.    O'Neil JT, Wang ML, Kim N, Maltenfort M, Ilyas AM. Prospective Evaluation of Opioid Consumption After Distal Radius Fracture Repair Surgery. Am J Orthop (Belle Mead NJ). 2017 Jan/Feb;46(1):E35-E40. PubMed PMID: 28235120.
26.    Stull J, Bhat S, Miller AJ, Hoffman R, Wang ML. Treatment of Atypical Compartment Syndrome Due to Proteus Infection. Orthopedics. 2017 Jan 1;40(1):e176-e178. PubMed PMID: 27684079.
27.    Wang ML, Hoffler CE, Ilyas AM, Kirkpatrick WH, Beredjiklian PK, et al. Hand Surgery and Fluoroscopic Eye Radiation Dosage: A Prospective Pilot Comparison of Large Versus Mini C-Arm Fluoroscopy Use. Hand (N Y). 2017 Jan;12(1):21-25. PubMed PMID: 28082838; PubMed Central PMCID: PMC5207279.
28.    Wang, M.L. and Vosbikian, M. (2016) Controversies in the Management of Chronic Non-Degenerative Scapholunate Instability. World Clinics in Orthopaedics:  Hand Surgery, A. Ilyas ed. Philadelphia, PA: Jaybee Medical Press.
29.    Kim N, Matzon JL, Abboudi J, Jones C, Kirkpatrick W, et al. A Prospective Evaluation of Opioid Utilization After Upper-Extremity Surgical Procedures: Identifying Consumption Patterns and Determining Prescribing Guidelines. J Bone Joint Surg Am. 2016 Oct 19;98(20):e89. PubMed PMID: 27869630.
30.    Wang ML, Miller AJ, Ballard BL, Botte MJ. Management of Snapping Scapula Syndrome. Orthopedics. 2016 Jul 1;39(4):e783-6. PubMed PMID: 27280624.
31.    Ketonis C, Kim N, Liss F, Zmistowski B, Matzon J, et al. Wide Awake Trigger Finger Release Surgery: Prospective Comparison of Lidocaine, Marcaine, and Exparel. Hand (N Y). 2016 Jun;11(2):177-83. PubMed PMID: 27390559; PubMed Central PMCID: PMC4920533.
32.    Bhat S, Stull JD, Wang ML. Management of a Dermocutaneous Black Mold Abscess of the Finger with Flexor Sheath Involvement. JBJS Case Connect. 2016 Apr-Jun;6(2):e41. PubMed PMID: 29252674.
33.    Steplewski A, Fertala J, Beredjiklian PK, Abboud JA, Wang ML, et al. Auxiliary proteins that facilitate formation of collagen-rich deposits in the posterior knee capsule in a rabbit-based joint contracture model. J Orthop Res. 2016 Mar;34(3):489-501. PubMed PMID: 26241613.
34.    Steplewski A, Fertala J, Beredjiklian P, Wang ML, Fertala A. Matrix-specific anchors: a new concept for targeted delivery and retention of therapeutic cells. Tissue Eng Part A. 2015 Apr;21(7-8):1207-16. PubMed PMID: 25435302; PubMed Central PMCID: PMC4394883.
35.    Wang ML, Beredjiklian PK. Management of radial head fracture with elbow dislocation. J Hand Surg Am. 2015 Apr;40(4):813-6. PubMed PMID: 25499845.
36.    Wang ML, Vosbikian MM, Abboudi J, Beredjiklian PK. Treatment of a Chronic Multidrug-Resistant Cutaneous Mycobacterium chelonae Infection of the Hand with Wide Debridement and Skin-Grafting: A Case Report. JBJS Case Connect. 2014 Oct/Dec/Nov;4(4):e102. PubMed PMID: 29252770.
37.    Wang ML, Bednar JM. Lunatocapitate and triquetrohamate arthrodeses for degenerative arthritis of the wrist. J Hand Surg Am. 2012 Jun;37(6):1136-41. PubMed PMID: 22624782.
38.    Wang ML, Ballard BL, Kulidjian AA, Abrams RA. Upper extremity reconstruction with a humeral tumor endoprosthesis: a novel salvage procedure after multiple revisions of total shoulder and elbow replacements. J Shoulder Elbow Surg. 2011 Jan;20(1):e1-8. PubMed PMID: 21134657.
39.    Tran W, Foran J, Wang M, Schwartz A. Postsurgical bleeding following treatment of a chronic Morel-LavallĂ©e lesion. Orthopedics. 2008 Aug;31(8):814. PubMed PMID: 19292405.
40.    Wang ML, Massie J, Allen RT, Lee YP, Kim CW. Altered bioreactivity and limited osteoconductivity of calcium sulfate-based bone cements in the osteoporotic rat spine. Spine J. 2008 Mar-Apr;8(2):340-50. PubMed PMID: 17983844.
41.    Vecchio KS, Zhang X, Massie JB, Wang M, Kim CW. Conversion of bulk seashells to biocompatible hydroxyapatite for bone implants. Acta Biomater. 2007 Nov;3(6):910-8. PubMed PMID: 17684000.
42.    Vecchio KS, Zhang X, Massie JB, Wang M, Kim CW. Conversion of sea urchin spines to Mg-substituted tricalcium phosphate for bone implants. Acta Biomater. 2007 Sep;3(5):785-93. PubMed PMID: 17512809.
43.    Wang ML, Massie J, Perry A, Garfin SR, Kim CW. A rat osteoporotic spine model for the evaluation of bioresorbable bone cements. Spine J. 2007 Jul-Aug;7(4):466-74. PubMed PMID: 17630145.
44.    Wang ML, Sharkey PF, Tuan RS. Particle bioreactivity and wear-mediated osteolysis. J Arthroplasty. 2004 Dec;19(8):1028-38. PubMed PMID: 15586339.
45.    Wang ML, Tuli R, Manner PA, Sharkey PF, Hall DJ, et al. Direct and indirect induction of apoptosis in human mesenchymal stem cells in response to titanium particles. J Orthop Res. 2003 Jul;21(4):697-707. PubMed PMID: 12798071.
46.    Tuli R, Seghatoleslami MR, Tuli S, Wang ML, Hozack WJ, et al. A simple, high-yield method for obtaining multipotential mesenchymal progenitor cells from trabecular bone. Mol Biotechnol. 2003 Jan;23(1):37-49. PubMed PMID: 12611268.
47.    Tuli R, Tuli S, Nandi S, Wang ML, Alexander PG, et al. Characterization of multipotential mesenchymal progenitor cells derived from human trabecular bone. Stem Cells. 2003;21(6):681-93. PubMed PMID: 14595128.
48.    Wang ML, Nesti LJ, Tuli R, Lazatin J, Danielson KG, et al. Titanium particles suppress expression of osteoblastic phenotype in human mesenchymal stem cells. J Orthop Res. 2002 Nov;20(6):1175-84. PubMed PMID: 12472226.
49.    Nesti LJ, Caterson EJ, Wang M, Chang R, Chapovsky F, et al. TGF-beta1 calcium signaling increases alpha5 integrin expression in osteoblasts. J Orthop Res. 2002 Sep;20(5):1042-9. PubMed PMID: 12382972.
50.    Nesti LJ, Caterson EJ, Wang M, Chang R, Chapovsky F, et al. TGF-beta1-stimulated osteoblasts require intracellular calcium signaling for enhanced alpha5 integrin expression. Ann N Y Acad Sci. 2002 Jun;961:178-82. PubMed PMID: 12081894.
51.    Wang ML, Hauschka PV, Tuan RS, Steinbeck MJ. Exposure to particles stimulates superoxide production by human THP-1 macrophages and avian HD-11EM osteoclasts activated by tumor necrosis factor-alpha and PMA. J Arthroplasty. 2002 Apr;17(3):335-46. PubMed PMID: 11938511.

 

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